About Us
PLL THERAPEUTICS
PLL Therapeutics, a clinical-stage biopharmaceutical company, is developing an innovative drug and diagnostics to provide both a treatment and follow-up of patients living with the neurodegenerative disease ALS. The company’s platform technology is also set up for neurological pathologies, such as Parkinson’s and Alzheimer’s diseases.
Brief History
Acquired in mid-2018, PLL Therapeutics has assembled an experienced management team in 2019 to lead the company to success with our new assets.
PLL Therapeutics has developed a total solution approach to treat neurodegenerative and autoimmune diseases at the root of the disease by combining early and companion diagnostics with multi-target therapeutic treatments.
Mission & vision
- PLL THERAPEUTICS has 3 mains patents family
1) Defensive patent families 2 patents
To protect our asset in ALS, Stroke…
2) Diagnosis patent families 3 patents 2 patents pending
To protect our strategy, early stage and companion diagnostic
on Neurodegenerative, auto immune and Proliferative disease
3) Product patent families 4 patents
In the treatment of Neurodegenerative and Autoimmune disease where our main target is linked to gut permeability as initialization and chronicity of such disease.
Protection of our API and DP manufacturing
- Success of pre-clinical studies & key learnings
The dysbiosis link to gut microbiota and gut permeability by releasing in the body “components” as chemicals, bacteria represent 90% of the origin of neurodegenerative diseases as ALS in association with genetic effect. To target such side effect at an early stage as PLL Therapeutics diagnostic kit and therapy will allow this will stop initialization and chronicity and well being of patient.
- Pharmaceutical GMP grade of our drug products allowing us to launch clinical phases in human
- Clinical trials Phase I/II on ALS will be launched in Australia in Q2 2024
- Ethics committee is currently validating our Investigation Medicinal Product Dossier (IMPD)
- Collaborative agreement with ALS patient association in Europe, United states and Australia.
Biographies
Jean-Pascal ZAMBAUX
co-founder & shareholder, CEO
Jean-Pascal has a strong track-record in the pharmaceutical and biotech industry.
He created Disposable-Lab, a CMO specializing in producing injectable drugs for clinical trials, where he served as CEO between 2008 and 2018, and successfully ran the first pharma company to use a single-use grade A isolator for fill ‘n’ finish. During a career spanning 30+ years, Jean-Pascal has implemented or has been a vanguard in many disruptive business models. He holds a Doctorate in Pharmacy (PharmD), earned from the University of Paris and the University of Reims, Champagne-Ardenne.
Michel LARROCHE
co-founder & shareholder
Since 2019, Michel has served as strategic advisor and investor in PLL Therapeutics and Ocean Kiss, a new wave of seafood. For more than 20+ years, Michel was CEO of MOM Mont Blanc, the international healthy snack fruit and dairy food business, where he grew US market revenues from $5M to $350M over a five-year period. Prior to that, he worked as Southern Europe managing director for H J Heinz. Michel has an engineering degree from AgroParisTech.
Mario PHILIPS
co-founder & shareholder
Mario served as CEO of Polyplus-Transfection and currently sits on the board of several life sciences companies. Mario’s decades of experience include roles as a strategic partner with ArchiMed, where he contributed his deep experience of the bioprocessing sector, and VP and general manager of Pall Biotech. There, he had full P&L responsibilities for the biotech BU within NYSE-listed Danaher and led the rapid expansion of the group’s core bioprocessing capabilities. Prior to Pall Biotech, Mr. Philips served as SVP and general manager of ATMI Life Sciences.
Joe BONCORE
new shareholder
Joe is the principal and founder of Commonwealth Counsel, where he works with some of Massachusetts’ top non-profits, philanthropic leaders and corporations. Before that, Joe was CEO of the Massachusetts Biotechnology Council (MassBio), where he led efforts to advance Massachusetts’ leadership as the #1 life sciences cluster in the world. Prior to joining MassBio, Joe served as the state senator for several districts in Massachusetts. He has a bachelor’s degree in political science and government from Providence College and received his juris doctorate from the Massachusetts School of Law.
Team members
Souad KECHAIRI
Chief Medical Officer
MD and MSc in Neurosciences.
+25Y of international medical and research experience in CRO and pharma industry.
European and Global Clinical Research trial conduct with increasing responsibility in clinical development and pharmacovigilance
Lara ROSENBERG
Chief Financial Officer, HR Management
+15 Y exp. in Finance and Human Resources.
MSc in Human and Social Sciences at Bordeaux university.
Sébastien DULEU
Scientific and Technical Manager Diagnostic Department
+20Y exp. in Diagnostics development.
MSc in Molecular Immunology & Parasitology at Bordeaux University.
Cyril FÉRANDON
Therapy project coordinator
PhD Medical Biology specialty in Immunology-Microbiology. Scientist, technical support and coordinator in PLL Therapeutics. Expertise in Molecular Biology, Biochemistry, fungal biotechnology.
Scientific Board Members
Didier COQUOZ : Chief Regulatory Officer. +30Y exp. in Pharma companies as founder, CEO, CBDO, R&D manager, etc.
Pierre MORGON: CEO of MRGN Advisors, CBO at Nuvamid, and Regional Partner for Switzerland at Merieux Equity Partners.
Megan ROBERTSON: MBBS FRACP FANZCA FCICM. Group Chief Research Officer, St Vincent’s Health Australia
Jean-Michel ROUILLON: Clinical Gastroenterologist
Partners
Our CRO : ALITHIA Life Sciences
Our CDMO : CURAPATH
Scientific Advisory Board
Already launched with key player in NeuroSciences and reglementary field Will be presented shortly
LEADERSHIP
CEO : Dr Jean Pascal Zambaux
Board of Director : Mario Philips | Michel Larroche
New shareholder : Joe Boncore
PLL THERAPEUTICS